How many children did Thanos have?

Could you please clarify for me the context in which you're asking about Thanos' children? Are we referring to the Marvel Cinematic Universe's portrayal of Thanos, or perhaps a different iteration of the character from the comics? In the MCU, Thanos is depicted as having two adopted daughters, Gamora and Nebula, who play significant roles in his quest for the Infinity Stones. However, if we're discussing the comics, the situation may differ. Could you provide more specific details or clarify your question further?